Decoding the Enigma of Hypothyroidism in Pregnancy
The Source Article Details
Burden, risk factors and outcomes associated with adequately treated hypothyroidism in a population-based cohort of pregnant women from North India by Neeta Dhabhai et al. in 2023.
The Source Article's Abstract
Hypothyroidism is the commonest endocrine disorder of pregnancy, with known adverse feto-maternal outcomes. The study aims to ascertain the burden, risk factors, and impact of treatment on adverse pregnancy outcomes in a population-based cohort of pregnant women in North Delhi, India.
The Source Article References
- Study of thyroid function in pregnancy, its feto-maternal outcome; a prospective observational study by K Mahadik, 2020 in BMC pregnancy and childbirth
- Perceptions of pregnant women of reasons for late initiation of antenatal care: a qualitative interview study. by D Warri, 2020 in BMC pregnancy and childbirth
- Hypothyroidism in pregnancy. by W Teng, 2013 in The lancet Diabetes & endocrinology
- Prevalence of thyroid dysfunction among women during the first trimester of pregnancy at a tertiary care hospital in Haryana by R Rajput, 2015 in Indian journal of endocrinology and metabolism
- Thyroid function during pregnancy in a multiethnic population in Norway by L Sletner, 2021 in Journal of the Endocrine Society
- The prevalence of thyroid disorders during early pregnancy in China: the benefits of universal screening in the first trimester of pregnancy by W Wang, 2011 in European journal of endocrinology
- Prevalence of Hypothyroidism in Pregnant Women in India: A Meta-Analysis of Observational Studies by V Yadav, 2021 in Journal of thyroid research
- Prevalence of hypothyroidism in pregnancy: An epidemiological study from 11 cities in 9 states of India by DK Dhanwal, 2016 in Indian journal of endocrinology and metabolism
- Reference Intervals for TSH on the Architect Analyser Based on the National Academy of Clinical Biochemistry (NACB) Guidelines Derived from Healthy Multi-Ethnic Asians Attending a Community Health Fair. by T Aw, 2019 in Int Arch Endocrinol Clin Res
- Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline by L De Groot, 2012 in The Journal of clinical endocrinology and metabolism
- 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. by EK Alexander, 2017 in Thyroid: official journal of the American Thyroid Association
- A Systematic Review on Normative Values of Trimester-specific Thyroid Function Tests in Indian Women by S Kannan, 2018 in Indian journal of endocrinology and metabolism
- Impact of an integrated nutrition, health, water sanitation and hygiene, psychosocial care and support intervention package delivered during the pre- and peri-conception period and/or during pregnancy and early childhood on linear growth of infants in the first two years of life, birth outcomes and nutritional status of mothers: study protocol of a factorial, individually randomized controlled trial in India. by S Taneja, 2020 in Trials
- TSH Comparison Between Chemiluminescence (Architect) and Electrochemiluminescence (Cobas) Immunoassays: An Indian Population Perspective. by R. Sarkar, 2014 in Indian journal of clinical biochemistry: IJCB.
- Levothyroxine and the risk of adverse pregnancy outcomes in women with subclinical hypothyroidism: a systematic review and meta-analysis. by M Bein, 2021 in BMC endocrine disorders
- Pregnancy Outcomes among Obese Pregnant Women with Hypothyroidism: Medical Record Review of a Single Tertiary Center in Saudi Arabia by AM Fallatah, 2020 in Cureus
- Maternal thyroid function, prepregnancy obesity and gestational weight gain-The Generation R Study: A prospective cohort study by FM Collares, 2017 in Clinical endocrinology
- The Impact of Obesity on Thyroid Autoimmunity and Dysfunction: A Systematic Review and Meta-Analysis. by RH Song, 2019 in Frontiers in immunology
- Prevalence of hypothyroidism amongst pregnant women: a study done in rural set up. by NS Pillai, 2018 in International Journal of Reproduction, Contraception, Obstetrics and Gynecology.
- Iron Deficiency, a Risk Factor of Thyroid Disorders in Reproductive-Age and Pregnant Women: A Systematic Review and Meta-Analysis. by J Luo, 2021 in Frontiers in endocrinology
Citing the Source Article (APA)
Dhabhai, N., Chowdhury, R., Virmani, A., Chaudhary, R., Taneja, S., Mittal, P., Dewan, R., Dang, A., Kaur, J., Bhandari, N. (2023). Burden, risk factors and outcomes associated with adequately treated hypothyroidism in a population-based cohort of pregnant women from North India. PLoS ONE, 18(9), e0282381-e0282381. 10.1371/journal.pone.0282381
The Scope and Scale
The study is an observational analysis focusing on pregnant women in North Delhi, India. It aims to understand the prevalence, risk factors, and outcomes of hypothyroidism.
With a sample size of 2317 women, the study is comprehensive and offers valuable insights.
- 29.2% of the women had hypothyroidism.
- Overweight or obesity increased the risk.
- Higher hemoglobin levels decreased the risk.
Implications for Medical Practice
Early screening and adequate treatment are crucial. The study shows that with proper care, adverse pregnancy outcomes can be avoided.
This study is a wake-up call for healthcare providers. It emphasizes the need for universal TSH screening and adequate treatment.
What are your thoughts on the impact of hypothyroidism on pregnancy? Do you think universal screening should be mandatory? Leave your comments below.