The Weighty Issue of Eye Health: A Closer Look
Recent research has shed light on a significant health concern: the impact of excessive body weight on intraocular pressure (IOP), a key factor in the development of glaucoma. This systematic review and meta-analysis delves into the correlation between obesity and increased IOP, offering insights crucial for both patients and healthcare professionals.
The Source Article Details
Role of excessive weight in intraocular pressure: a systematic review and meta-analysis by Noro Waspodo et al. in 2023.
The Source Article's Abstract
This systematic review and meta-analysis aimed to analyse the effect of excess body weight on intraocular pressure (IOP) values.
Method and Analysis
A literature search from PubMed, Medline and ScienceDirect Databases on 18 May 2023 was conducted by three reviewers, then filtered each study based on inclusion and exclusion criteria. For the quality assessment of included studies, the Newcastle-Ottawa Scale was adapted. Meta-analysis was performed using RevMan V.5.4 by entering the IOP values of each group to measure the mean difference.
From 2656 studies, there were 9 studies that matched the criteria and then were included to perform a quantitative meta-analysis. The results showed a mean difference of 0.93 (95% CI: 0.67 to 1.18) of the excessive weight group against the normal weight group. This suggests that there is a significant relationship between excess body weight and increasing values of IOP.
It can be concluded that excessive body weight tends to lead to higher IOP, which means that high IOP becomes a major risk factor for glaucoma.
The Source Article References
- Contact lens sensors in ocular diagnostics by Farandos, 2015 in Adv Healthc Mater
- Modifiable factors in the management of glaucoma: a systematic review of current evidence by Hecht, 2017 in Graefes Arch Clin Exp Ophthalmol
- Effects of body mass index on intraocular pressure and ocular pulse amplitude by Karadag, 2012 in Int J Ophthalmol
- Systemic and ocular determinants of mean ocular perfusion pressure in a population-based sample by Çakmak, 2020 in Jpn J Ophthalmol
- The association between Adiposity and the risk of glaucoma: a meta-analysis by Liu, 2017 in J Ophthalmol
- Evaluation of intraocular pressure and retinal nerve fiber layer, retinal ganglion cell, central macular thickness, and Choroidal thickness using optical coherence tomography in obese children and healthy controls by Baran, 2019 in Niger J Clin Pract
- Ocular abnormalities in morbid obesity by Teberik, 2019 in Arq Bras Oftalmol
- Correlation between body mass index and ocular parameters by Panon, 2019 in Clin Ophthalmol
- Evaluation of choroidal perfusion changes in obese patients: ocular effects of insulin resistance by Öner, 2018 in Arq Bras Oftalmol
- Effects of obesity on retrobulbar flow hemodynamics: color doppler ultrasound evaluation by Çekiç, 2017 in Arq Bras Oftalmol
- Blood pressure, ocular perfusion pressure, and body mass index in glaucoma patients by Ngo, 2013 in Eur J Ophthalmol
- The influence of retrobulbar Adipose tissue volume upon intraocular pressure in obesity by Stojanov, 2013 in Vojnosanit Pregl
- The relationship between body mass index and intra-ocular pressure in port Harcourt Nigeria by Pedro-Egbe, 2013 in BJMMR
- Correlation between ocular pulse amplitude measured by dynamic contour tonometer and visual field defects by Vulsteke, 2008 in Graefes Arch Clin Exp Ophthalmol
- The ability of nitric oxide to lower intraocular pressure is dependent on Guanylyl cyclase by Muenster, 2017 in Invest Ophthalmol Vis Sci
- Evaluation of the intraocular pressure in obese adolescents by Koçak, 2015 in Minerva Pediatr
- The relationship between components of metabolic syndrome and open-angle glaucoma by Newman-Casey, 2011 in Ophthalmology
- Underweight is a risk factor for atrial fibrillation: a nationwide population-based study by Kang, 2016 in Int J Cardiol
- Relationship of obesity and related disorders with ocular parameters in children and adolescent by Hazar, 2021 in Curr Eye Res
Citing the Source Article (APA)
Waspodo, N., Giffari Makkaraka, M.A., Nislawati, R., Ismail, A., Taufik Fadillah Zainal, A., Lolok, G.B. (2023). Role of excessive weight in intraocular pressure: a systematic review and meta-analysis. BMJ Open Ophthalmology, 8(1), e001355-e001355. 10.1136/bmjophth-2023-001355
Methodology and Findings: A Rigorous Approach
The study meticulously analyzed data from a wide range of sources, ensuring a comprehensive and reliable conclusion. The findings are alarming: excessive weight is strongly linked to higher IOP levels, suggesting a direct correlation between obesity and the risk of glaucoma.
- Increased Risk: The analysis indicates a mean difference of 0.93 in IOP values between individuals with excessive weight and those with normal weight.
- Implications for Health: These results underscore the importance of weight management in preventing ocular hypertension and, consequently, glaucoma.
Understanding the Impact: Beyond the Numbers
Glaucoma, often termed the “silent thief of sight,” is the second leading cause of irreversible blindness. This study’s revelations about weight and IOP offer a new perspective on preventing this devastating condition.
PP-ICONS Analysis: A Deeper Insight
Given the nature of this systematic review and meta-analysis, it’s essential to evaluate its impact using the PP-ICONS approach:
- Problem: The study addresses the problem of increased IOP due to excessive weight, a major risk factor for glaucoma.
- Patient: The focus is on individuals with excessive body weight.
- Intervention: The intervention in this context is weight management and its impact on IOP.
- Comparison: The study compares IOP values between individuals with excessive weight and those with normal weight.
- Outcome: The outcome is a better understanding of the relationship between weight and IOP, leading to improved glaucoma prevention strategies.
- Number Needed to Treat (NNT): As a systematic review and meta-analysis, NNT is not directly applicable.
Join the Discussion
What are your thoughts on the relationship between body weight and eye health? How can this information be utilized in clinical practice to better prevent glaucoma? Share your insights and experiences in the comments below.