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Home / Why Your Gums Could Be a Window to Your Vascular Health

Why Your Gums Could Be a Window to Your Vascular Health

Cohort Study
Review by Daniel Chase on December 8, 2023.
Dentistry (miscellaneous), Oral Surgery, Periodontics
Why Your Gums Could Be a Window to Your Vascular Health
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Oral Health: More Than Just a Pretty Smile

When we think of oral health, we often think of pearly white teeth and fresh breath. But what if your mouth could reveal more about your overall health? A recent pilot study published in Frontiers in Oral Health suggests just that.

The study investigates the impact of oral inflammatory load (OIL) on vascular function in young adults. It’s a groundbreaking exploration that could have significant implications for cardiovascular health.

Full Article

The Source Article Details

Oral inflammatory load predicts vascular function in a young adult population: a pilot study by Ker-Yung Hong et al. in 2023.

The Source Article's Abstract

Background

The periodontium is a highly vascularized area of the mouth, and periodontitis initiates negative functional and structural changes in the vasculature. The purpose of this pilot study is to investigate the effects of objectively measured whole mouth oral inflammatory load (OIL) on vascular function in apparently healthy individuals.

The Source Article References

  • Global prevalence of periodontal disease and lack of its surveillance by Nazir, 2020 in Sci World J
  • Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients by Higashi, 2008 in Am Heart Assoc
  • Active gingival inflammation is linked to hypertension by Pietropaoli, 2020 in J Hypertens
  • Role of nitric oxide in inflammatory diseases by Sharma, 2007 in Inflammopharmacology
  • Acute systemic inflammation increases arterial stiffness and decreases wave reflections in healthy individuals by Vlachopoulos, 2005 in Am Heart Assoc
  • Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation by Amar, 2003 in Arterioscler Thromb Vasc Biol
  • Prevalence of periodontal pathogens in subgingival lesions, atherosclerotic plaques and healthy blood vessels: a preliminary study by Elkaïm, 2008 in J Periodontal Res
  • Periodontal diseases : pathogenesis nitric oxide synthesis and severity of human periodontal disease by Batista, 2002 in Oral Dis
  • Quantifying oral inflammatory load: oral neutrophil counts in periodontal health and disease by Landzberg, 2015 in J Periodontal Res
  • Oral inflammatory load: neutrophils as oral health biomarkers by Khoury, 2020 in J Periodontal Res
  • Oral neutrophil levels: a screening test for oral inflammatory load in pregnancy in a medical setting by Huda, 2015 in J Periodontol
  • Evaluation of periodontal disease and oral inflammatory load in adults with special needs using oral neutrophil quantification by Moosani, 2014 in Spec Care Dentist
  • Degree of gingivitis correlates to systemic inflammation parameters by Wohlfeil, 2009 in Clin Chim Acta
  • Gingivitis, dental caries and tooth loss: risk factors for cardiovascular diseases or indicators of elevated health risks by Ylöstalo, 2006 in J Clin Periodontol
  • Time course analysis of brachial artery flow mediated dilatation in subjects with gingival inflammation by Carallo, 2014 in Int Angiol
  • Periodontal disease and coronary heart disease by Hujoel, 2000 in J Am Med Assoc
  • Novel rinse assay for the quantification of oral neutrophils and the monitoring of chronic periodontal disease by Bender, 2006 in J Periodontal Res
  • The neutrophil: constant defender and first responder by Fine, 2020 in Front Immunol
  • Oral and blood neutrophil activation states during experimental gingivitis by Wellappuli, 2018 in JDR Clin Trans Res
  • Arterial stiffness and pulse wave reflection are increased in patients suffering from severe periodontitis by Jockel-Schneider, 2014 in PLoS One

Citing the Source Article (APA)

Hong, K., Ghafari, A., Mei, Y., Williams, J.S., Attia, D., Forsyth, J., Wang, K., Wyeld, T., Sun, C., Glogauer, M., King, T.J. (2023). Oral inflammatory load predicts vascular function in a young adult population: a pilot study. Frontiers in Oral Health, 4, 1233881-1233881. 10.3389/froh.2023.1233881

What’s OIL Got to Do With It?

OIL, or oral inflammatory load, is a measure of inflammation in the mouth. The study used oral neutrophil counts as an objective measure for OIL. Neutrophils are white blood cells that play a crucial role in inflammation.

Why does this matter? Because inflammation in the mouth could be a predictor of vascular function and, by extension, cardiovascular health. The study found that higher OIL levels were associated with lower flow-mediated dilation, an indicator of vascular health.

Young Hearts, Big Implications

The study focused on an otherwise healthy young adult population aged 18-30. This is significant because most research in this area has been conducted on older populations with more health complications.

By focusing on a younger demographic, the study could isolate the effects of OIL on vascular function, making the findings more robust and potentially more alarming.

FAQs: What You Need to Know

  • What is OIL? – Oral Inflammatory Load, a measure of inflammation in the mouth.
  • How was it measured? – Using oral neutrophil counts.
  • Who participated in the study? – Young adults aged 18-30.
  • What were the key findings? – Higher OIL levels were associated with lower vascular function.

Given the study’s findings, the importance of maintaining oral health extends beyond aesthetics and comfort. It could be a window into your cardiovascular health, a leading cause of death globally. So, you might want to reconsider the next time you think about skipping that dental appointment.

What are your thoughts on the relationship between oral health and cardiovascular function? Could this study change the way we approach oral hygiene? Share your thoughts below.

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Tags: Cardiovascular RiskOral InflammationPilot StudyVascular FunctionYoung Adults

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